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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PKN3 All Species: 33.33
Human Site: S60 Identified Species: 52.38
UniProt: Q6P5Z2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P5Z2 NP_037487.2 889 99421 S60 V Q Q L L R S S N R R L E Q L
Chimpanzee Pan troglodytes XP_001159776 886 99121 S60 V Q Q L L R S S N R R L E Q L
Rhesus Macaque Macaca mulatta XP_001110500 1011 111864 S173 V Q Q L L Q S S N R R L E Q L
Dog Lupus familis XP_548434 951 104664 S122 V Q Q L L R S S N R R L E Q L
Cat Felis silvestris
Mouse Mus musculus Q8K045 878 97863 S57 V Q Q L L R A S N R R L E Q L
Rat Rattus norvegicus O08874 985 112050 S89 V D N I L K K S N K K L E E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506565 993 109767 S162 V E R L L R S S N R K L E Q L
Chicken Gallus gallus XP_422357 1013 114806 S117 V D N I L K K S N K K L E D L
Frog Xenopus laevis Q7ZX15 486 56292
Zebra Danio Brachydanio rerio XP_697542 940 106140 S72 V D G Q L R A S S R K L E Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13678 634 71138
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34885 707 80133 V40 T A A I D S Y V N V D W D E Y
Sea Urchin Strong. purpuratus XP_787090 799 90414 V38 G E K E A G E V S D M G F R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P24583 1151 131500 A47 C N T N I R E A R Q N L E Y L
Red Bread Mold Neurospora crassa P87253 1142 127954 G47 L D T Q M R E G R R N L E F F
Conservation
Percent
Protein Identity: 100 97.7 81.5 84.2 N.A. 83.2 49.9 N.A. 64.2 48.9 26.2 52.2 N.A. 28 N.A. 29.1 41.5
Protein Similarity: 100 97.8 82.9 87.6 N.A. 88.4 63.6 N.A. 72.9 63 36.6 67.6 N.A. 41.5 N.A. 43.9 58.2
P-Site Identity: 100 100 93.3 100 N.A. 93.3 46.6 N.A. 80 46.6 0 60 N.A. 0 N.A. 6.6 0
P-Site Similarity: 100 100 100 100 N.A. 100 80 N.A. 100 73.3 0 80 N.A. 0 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 25.2 27.1
Protein Similarity: N.A. N.A. N.A. N.A. 41.7 43.2
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 26.6
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 40
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 0 7 0 14 7 0 0 0 0 0 0 0 % A
% Cys: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 27 0 0 7 0 0 0 0 7 7 0 7 7 0 % D
% Glu: 0 14 0 7 0 0 20 0 0 0 0 0 74 14 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 7 7 7 % F
% Gly: 7 0 7 0 0 7 0 7 0 0 0 7 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 20 7 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 7 0 0 14 14 0 0 14 27 0 0 0 0 % K
% Leu: 7 0 0 40 60 0 0 0 0 0 0 74 0 0 67 % L
% Met: 0 0 0 0 7 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 7 14 7 0 0 0 0 60 0 14 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 34 34 14 0 7 0 0 0 7 0 0 0 47 0 % Q
% Arg: 0 0 7 0 0 54 0 0 14 54 34 0 0 7 7 % R
% Ser: 0 0 0 0 0 7 34 60 14 0 0 0 0 0 0 % S
% Thr: 7 0 14 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 60 0 0 0 0 0 0 14 0 7 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 0 0 0 0 0 0 7 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _